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Article

Mouse striatal dopamine nerve terminals express alpha4alpha5beta2 and two stoichiometric forms of alpha4beta2*-nicotinic acetylcholine receptors.

Journal of molecular neuroscience : MN - 1 Jan 2010

Grady Sharon R, Salminen Outi, McIntosh J Michael, Marks Michael J, Collins Allan C

Abstract excerpt

Wild-type and alpha5 null mutant mice were used to identify nicotinic cholinergic receptors (nAChRs) that mediate alpha-conotoxin MII (alpha-CtxMII)-resistant dopamine (DA) release from striatal synaptosomes. Concentration-effect curves for ACh-stimulated release (20 s) were monophasic when wild-type synaptosomes were assayed but biphasic with synaptosomes from the alpha5 null mutant. Deleting the alpha5 gene...

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Share to Acetylcholine
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nicotinic Antagonists

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Share to Receptors, Nicotinic

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Source

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Identifiers

PMID: 19693710
DOI: 10.1007/s12031-009-9263-y
PMCID: PMC4386732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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