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Article

An expandable, inducible hemangioblast state regulated by fibroblast growth factor.

Stem cell reports - 9 Dec 2014

Vereide David T, Vickerman Vernella, Swanson Scott A, Chu Li-Fang, McIntosh Brian E, Thomson James A

Abstract excerpt

During development, the hematopoietic and vascular lineages are thought to descend from common mesodermal progenitors called hemangioblasts. Here we identify six transcription factors, Gata2, Lmo2, Mycn, Pitx2, Sox17, and Tal1, that "trap" murine cells in a proliferative state and endow them with a hemangioblast potential. These "expandable" hemangioblasts (eHBs) are capable, once released from the control of the...

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Identifiers

PMID: 25458896
DOI: 10.1016/j.stemcr.2014.10.003
PMCID: PMC4264065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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