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Article

A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A.

Biochemical and biophysical research communications - 12 Dec 2014

Dzialo Maria C, Travaglini Kyle J, Shen Sean, Loo Joseph A, Clarke Steven G

Abstract excerpt

The elongation factors of Saccharomyces cerevisiae are extensively methylated, containing a total of ten methyllysine residues. Elongation factor methyltransferases (Efm1, Efm2, Efm3, and Efm4) catalyze at least four of these modifications. Here we report the identification of a new type of protein lysine methyltransferase, Efm5 (Ygr001c), which was initially classified as N6-adenine DNA methyltransferase-like....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25446118
DOI: 10.1016/j.bbrc.2014.11.022
PMCID: PMC4263273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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