Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase.

The Journal of biological chemistry - 12 Feb 2016

Owings Joshua P, Kuiper Emily G, Prezioso Samantha M, Meisner Jeffrey, Varga John J, Zelinskaya Natalia, Dammer Eric B, Duong Duc M, Seyfried Nicholas T, Albertí Sebastián, Conn Graeme L, Goldberg Joanna B

Abstract excerpt

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that trimethylates elongation factor-thermo-unstable (EF-Tu) on lysine 5. Lysine 5 methylation occurs in a temperature-dependent manner and is generally only seen when P. aeruginosa is grown at temperatures close to ambient (25 °C) but not at higher temperatures (37 °C). We have previously identified the gene, eftM (for EF-Tu-modifying enzyme),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Enzyme Stability
Share to Lysine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Methylation

Share to Peptide Elongation Factor Tu

Share to Protein Methyltransferases

Share to Protein Unfolding

Share to Pseudomonas aeruginosa

Share to S-Adenosylmethionine

Source

Open in PubMed Open full text

Identifiers

PMID: 26677219
DOI: 10.1074/jbc.M115.706853
PMCID: PMC4751374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase.PMID 26677219Read ↗

The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infectionSemantic proximity Read ↗

A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A.Semantic proximity Read ↗

A new target of multiple lysine methylation in bacteriaSemantic proximity Read ↗

The interactome of <i>Cryptococcus neoformans</i> Rmt5 reveals multiple regulatory points in fungal cell biology and pathogenesisSemantic proximity Read ↗

Epigenetic regulation in prokaryotes: transcriptional and phenotypic outcomes of DNA methyltransferase activity.Semantic proximity Read ↗

16S rRNA methyltransferase KsgA contributes to oxidative stress and antibiotic resistance in Pseudomonas aeruginosa.Semantic proximity Read ↗

Ribosomal A site binding pattern differs between Arm methyltransferases from clinical pathogens and a natural producer of aminoglycosides.Semantic proximity Read ↗

Methyltransferase Erm(37) Slips on rRNA to Confer Atypical Resistance in Mycobacterium tuberculosisSemantic proximity Read ↗

Identification of a Pseudomonas aeruginosa PAO1 DNA Methyltransferase, Its Targets, and Physiological RolesSemantic proximity Read ↗

Mycobacterium smegmatis Erm(38) is a reluctant dimethyltransferase.Semantic proximity Read ↗

Unravelling post-transcriptional PrmC-dependent regulatory mechanisms in Pseudomonas aeruginosa.Semantic proximity Read ↗

EfgA is a conserved formaldehyde sensor that halts bacterial translation in response to elevated formaldehydeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.