Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Repeat Region of the Circumsporozoite Protein is Critical for Sporozoite Formation and Maturation in Plasmodium

1 Dec 2014

Abstract excerpt

The circumsporozoite protein (CSP) is the major surface protein of the sporozoite stage of malaria parasites and has multiple functions as the parasite develops and then migrates from the mosquito midgut to the mammalian liver. The overall structure of CSP is conserved among Plasmodium species, consisting of a species-specific central tandem repeat region flanked by two conserved domains: the NH2-terminus and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Malaria Research and Control
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25438048
DOI: 10.1371/journal.pone.0113923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Repeat Region of the Circumsporozoite Protein is Critical for Sporozoite Formation and Maturation in PlasmodiumPMID 25438048Read ↗

<i>Plasmodium</i> Repetome: A mysterious space with a wealth of informationSemantic proximity Read ↗

Plasmodium Repetome: A mysterious space with a wealth of informationSemantic proximity Read ↗

Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodiesSemantic proximity Read ↗

Evolutionary dynamics of the immunodominant repeats of the Plasmodium vivax malaria-vaccine candidate circumsporozoite protein (CSP).Semantic proximity Read ↗

Dysfunctional memory B cell responses to the protective repeat region of the <i>Plasmodium</i> circumsporozoite protein are associated with waning humoral immunitySemantic proximity Read ↗

PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparumSemantic proximity Read ↗

Avid binding by B cells to the <i>Plasmodium</i> circumsporozoite protein repeat suppresses responses to protective subdominant epitopesSemantic proximity Read ↗

Repetitive sequences in malaria parasite proteinsSemantic proximity Read ↗

The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivoSemantic proximity Read ↗

Proteolytic Cleavage of the<i>Plasmodium falciparum</i>Circumsporozoite Protein Is a Target of Protective AntibodiesSemantic proximity Read ↗

Molecular and functional properties of human <i>Plasmodium falciparum</i> CSP C-terminus antibodiesSemantic proximity Read ↗

The N-terminus of <i>Plasmodium falciparum</i> Circumsporozoite Protein Contains Three Non-Overlapping Murine B-cell Epitope RegionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.