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Repetitive sequences in malaria parasite proteins

14 Sept 2017

Abstract excerpt

Five species of parasite cause malaria in humans with the most severe disease caused by Plasmodium falciparum. Many of the proteins encoded in the P. falciparum genome are unusually enriched in repetitive low-complexity sequences containing a limited repertoire of amino acids. These repetitive sequences expand and contract dynamically and are among the most rapidly changing sequences in the genome. The simplest...

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PMID: 29077880
DOI: 10.1093/femsre/fux046

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