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Article

Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Dec 2014

Severson Paul L, Vrba Lukas, Stampfer Martha R, Futscher Bernard W

Abstract excerpt

Genetic mutations are known to drive cancer progression and certain tumors have mutation signatures that reflect exposures to environmental carcinogens. Benzo[a]pyrene (BaP) has a known mutation signature and has proven capable of inducing changes to DNA sequence that drives normal pre-stasis hum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25435355
DOI: 10.1016/j.mrgentox.2014.10.011
PMCID: PMC4250937

Genes

FANCA
LCP1
LPP
MED12
PLCG1
TAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25435355-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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