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Article

Acute leukemias in children with Down syndrome.

Pediatric clinics of North America - 1 Feb 2008

Zwaan Michel C, Reinhardt Dirk, Hitzler Johann, Vyas Paresh

Abstract excerpt

Children with Down syndrome have an increased risk for developing both acute myeloid as well as lymphoblastic leukemia. These leukemias differ in presenting characteristics and underlying biology when compared with leukemias occurring in non-Down syndrome children. Myeloid leukemia in children with Down syndrome is preceded by a preleukemic clone (transient leukemia or transient myeloproliferative disorder),...

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Identifiers

PMID: 18242315
DOI: 10.1016/j.pcl.2007.11.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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