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Article

Profiling and identification of novel rpoB mutations in rifampicin-resistant Mycobacterium tuberculosis clinical isolates from Pakistan.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Nov 2021

Qadir Mehmood, Tahseen Sabira, McHugh Timothy D, Hussain Alamdar, Masood Faisal, Ahmed Niaz, Faryal Rani

Abstract excerpt

INTRODUCTION: Rifampicin (RIF) is one of the most effective anti-tuberculosis first-line drugs prescribed along with isoniazid. However, the emergence of RIF resistance Mycobacterium tuberculosis (MTB) isolates is a major issue towards tuberculosis (TB) control program in high MDR TB-burdened countries including Pakistan. Molecular data behind phenotypic resistance is essential for better management of RIF...

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Identifiers

PMID: 34244055
DOI: 10.1016/j.jiac.2021.06.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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