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Article

Pyrosequencing for rapid detection of tuberculosis resistance in clinical isolates and sputum samples from re-treatment pulmonary tuberculosis patients.

BMC infectious diseases - 13 Apr 2014

Zheng Ruijuan, Zhu Changtai, Guo Qi, Qin Lianhua, Wang Jie, Lu Junmei, Cui Haiyan, Cui Zhenling, Ge Baoxue, Liu Jinming, Hu Zhongyi

Abstract excerpt

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is a major public health problem. Early diagnosis of MDR-TB patients is essential for minimizing the risk of Mycobacterium tuberculosis (MTB) transmission. The conventional drug susceptibility testing (DST) methods for detection of drug-resistant M. tuberculosis are laborious and cannot provide the rapid detection for clinical practice. METHODS: The aim of...

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PMID: 24725975
DOI: 10.1186/1471-2334-14-200
PMCID: PMC4021344

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