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Article

Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease.

Current opinion in gastroenterology - 1 Jan 2015

Hosomi Shuhei, Kaser Arthur, Blumberg Richard S

Abstract excerpt

PURPOSE OF REVIEW: The purpose of this study is to provide an overview of the role of endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in inflammatory bowel disease (IBD). RECENT FINDINGS: Human genetic studies have identified several UPR-related genes and autophagy-related genes as IBD risk loci. Impairment of each branch of the UPR causes spontaneous enteritis or creates higher...

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Source

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Identifiers

PMID: 25426970
DOI: 10.1097/MOG.0000000000000144
PMCID: PMC4592163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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