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Article

Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis.

Current opinion in gastroenterology - 1 Jul 2010

Kaser Arthur, Martínez-Naves Eduardo, Blumberg Richard S

Abstract excerpt

PURPOSE OF REVIEW: To provide an overview of the emerging role of cellular stress responses in inflammatory bowel disease (IBD). RECENT FINDINGS: The unfolded protein response (UPR) is a primitive cellular pathway that is engaged when responding to endoplasmic reticulum stress and regulates autophagy. Highly secretory cells such as Paneth cells and goblet cells in the intestines are particularly susceptible to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20495455
DOI: 10.1097/MOG.0b013e32833a9ff1
PMCID: PMC4592137

Genes

ARG2
MUC2
ORMDL3
XBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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