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Article

Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with In Vivo Persistence.

mBio - 2 Aug 2016

Ben-Ami Ronen, Zimmerman Offer, Finn Talya, Amit Sharon, Novikov Anna, Wertheimer Noa, Lurie-Weinberger Mor, Berman Judith

Abstract excerpt

UNLABELLED: Candida glabrata causes persistent infections in patients treated with fluconazole and often acquires resistance following exposure to the drug. Here we found that clinical strains of C. glabrata exhibit cell-to-cell variation in drug response (heteroresistance). We used population analysis profiling (PAP) to assess fluconazole heteroresistance (FLC(HR)) and to ask if it is a binary trait or a...

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Identifiers

PMID: 27486188
DOI: 10.1128/mBio.00655-16
PMCID: PMC4981708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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