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Article

Comparative genomic and transcriptomic analyses unveil novel features of azole resistance and adaptation to the human host in Candida glabrata.

FEMS yeast research - 1 Feb 2018

Salazar Sara Barbosa, Wang Can, Münsterkötter Martin, Okamoto Michiyo, Takahashi-Nakaguchi Azusa, Chibana Hiroji, Lopes Maria Manuel, Güldener Ulrich, Butler Geraldine, Mira Nuno Pereira

Abstract excerpt

The frequent emergence of azole resistance among Candida glabrata strains contributes to increase the incidence of infections caused by this species. Whole-genome sequencing of a fluconazole and voriconazole-resistant clinical isolate (FFUL887) and subsequent comparison with the genome of the susceptible strain CBS138 revealed prominent differences in several genes documented to promote azole resistance in C....

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Source

Identifiers

PMID: 29087506
DOI: 10.1093/femsyr/fox079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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