Article
Proteomic analysis of experimentally induced azole resistance in Candida glabrata.
The Journal of antimicrobial chemotherapy - 1 Aug 2006
Rogers P David, Vermitsky John-Paul, Edlind Thomas D, Hilliard George M
Abstract excerpt
OBJECTIVES: The aim of the present study was to identify changes in the proteome of a laboratory-derived azole-resistant strain of Candida glabrata compared with its susceptible parent strain in an effort to identify proteins that are differentially expressed in association with azole resistance. METHODS: Soluble and membrane protein fractions were isolated from mutant strain F15 (fluconazole MIC>128 mg/L) and...
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