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Article

Interactions between copy number and expression level of genes involved in fluconazole resistance in Candida glabrata

1 Jan 2013

Abstract excerpt

OBJECTIVES: This study aimed to elucidate the relative involvement of drug resistance gene copy number and overexpression in fluconazole resistance in clinical C. glabrata isolates using a population-based approach. METHODS: Fluconazole resistance levels were quantified using the minimal inhibitory concentration (MIC) via Etest method. Both gene expression levels and gene copy number of CgCDR1, CgPDH1, CgERG11,...

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PMID: 24273749
DOI: 10.3389/fcimb.2013.00074

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