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Article

Ionizing irradiation inhibits keloid fibroblast cell proliferation and induces premature cellular senescence

26 Nov 2014

Abstract excerpt

Keloids are one of the common refractory conditions in dermatology and aesthetic plastic surgery. The most effective treatment is superficial radiotherapy followed by surgical removal. The rate of recurrence is strongly associated with the total dose of ionizing irradiation, and the underlying mechanism remains unclear. In this study, we used primary keloid fibroblasts (KFb) isolated from patient samples to...

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PMID: 25425417
DOI: 10.1111/1346-8138.12702

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