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Article

Repeated exposure of mouse dermal fibroblasts at a sub-cytotoxic dose of UVB leads to premature senescence: a robust model of cellular photoaging.

Journal of dermatological science - 1 Jan 2014

Zeng Ji-ping, Bi Bo, Chen Liang, Yang Ping, Guo Yu, Zhou Yi-qun, Liu Tian-yi

Abstract excerpt

BACKGROUND: Photoaging skin is due to accumulative effect of UV irradiation that mainly imposes its damage on dermal fibroblasts. To mimic the specific cellular responses invoked by long term effect of UVB, it is preferable to develop a photo-damaged model in vitro based on repeated UVB exposure instead of a single exposure. OBJECTIVE: To develop a photo-damaged model of fibroblasts by repeated UVB exposure...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24054498
DOI: 10.1016/j.jdermsci.2013.08.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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