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Article

MiR-23a/-24-induced gene silencing results in mesothelial cell integration of pancreatic cancer

25 Nov 2014

Abstract excerpt

BACKGROUND: Invasion of the surrounding tissue is part of the metastatic cascade. Here, we examined the invasion of pancreatic ductal adenocarcinoma (PDAC) cells into the mesothelial barrier and identified the related microRNA (miRNA) expression profiles. METHODS: The interactions between PDAC cells and mesothelial monolayers were characterised and quantified using a specific time-lapse videomicroscopy assay....

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PMID: 25422915
DOI: 10.1038/bjc.2014.587

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