Article

mir-218 modulates ARF6 expression and inhibits pancreatic ductal adenocarcinoma invasion

2020-10-01

Abstract excerpt

<h4>Background</h4> Pancreatic ductal adenocarcinoma is an extremely malignant disease with the majority of patients having metastatic disease upon diagnosis. Recently, it was shown the SLIT2 plays a regulatory role in melanoma invasion through the control of invadopodia. Therefore, we sought to determine the mechanism behind miR-218 inhibition of pancreatic cancer invasion. <h4>Methods</h4> mir-218 target genes...

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Literature Corpus work: d552bd06-fee5-5a4d-b929-ed124b3385c4
DOI: 10.1101/2020.09.29.319236

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