Article

Mammalian Pumilio Proteins Control Cellular Morphology, Migration, and Adhesion

2022-07-20

Abstract excerpt

Pumilio proteins are RNA-binding proteins that control mRNA translation and stability by binding to the 3’ UTR of target mRNAs. Mammals have two canonical Pumilio proteins, PUM1 and PUM2, which are known to act in many biological processes, including embryonic development, neurogenesis, cell cycle regulation and genomic stability. Here, we characterized a new role of both PUM1 and PUM2 in regulating cell morpholog...

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Literature Corpus work: 7f2ea368-bbed-5c67-926d-b708b8e9a99b
DOI: 10.1101/2022.07.19.500580

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