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Article

EP300—A miRNA‐regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas

30 Jun 2009

Abstract excerpt

Genetic and epigenetic alterations during development of pancreatic ductal adenocarcinomas (PDACs) are well known. This study investigates genetic and epigenetic data together with tumor biology to find specific alterations responsible for metastasis formation. Using 16 human PDAC cell lines in a murine orthotopic PDAC model, local infiltration and metastatic spread were assessed by standardized dissemination...

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PMID: 19569050
DOI: 10.1002/ijc.24695

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