Article
Novel mutations in the displacement loop of mitochondrial DNA are associated with acute lymphoblastic leukemia: a genetic sequencing study.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Yacoub Haitham Ahmed, Mahmoud Wael Mahmoud, El-Baz Hatim Alaa El-Din, Eid Ola Mohamed, ELfayoumi Refaat Ibrahim, Elhamidy Salem Mohamed, Mahmoud Maged M
Abstract excerpt
BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. MATERIALS AND METHODS: This study investigated alterations in the displacement loop (d-loop) region of mitochondrial DNA (mtDNA) as a risk factor and diagnostic biomarker for early detection and diagnosis of acute...
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