Article
New haplotypes of the ATP synthase subunit 6 gene of mitochondrial DNA are associated with acute lymphoblastic leukemia in Saudi Arabia.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Yacoub Haitham Ahmed, Mahmoud Wael Mahmoud, El-Baz Hatim Alaa-Eldeen El-Din, Eid Ola Mohamed, El-Fayoumi Refaat Ibrahim, Mahmoud Maged Mostafa, Harakeh Steve, Abuzinadah Osama Ha
Abstract excerpt
BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. AIM AND OBJECTIVES: This study investigated substitutions in the ATP synthase subunit 6 gene of mitochondrial DNA (mtDNA) as a potential diagnostic biomarker for early detection and diagnosis of acute lymphoblastic leukemia....
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