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Article

Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation.

Nucleic acids research - 16 Dec 2014

Allepuz-Fuster Paula, Martínez-Fernández Verónica, Garrido-Godino Ana I, Alonso-Aguado Sergio, Hanes Steven D, Navarro Francisco, Calvo Olga

Abstract excerpt

The Rpb4 and Rpb7 subunits of eukaryotic RNA polymerase II (RNAPII) participate in a variety of processes from transcription, DNA repair, mRNA export and decay, to translation regulation and stress response. However, their mechanism(s) of action remains unclear. Here, we show that the Rpb4/7 heterodimer in Saccharomyces cerevisiae plays a key role in controlling phosphorylation of the carboxy terminal domain...

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Source

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Identifiers

PMID: 25416796
DOI: 10.1093/nar/gku1227
PMCID: PMC4267648

Genes

SSU72

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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