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Article

Phosphorylation of the yeast Rpb1 C-terminal domain at serines 2, 5, and 7.

The Journal of biological chemistry - 25 Sept 2009

Kim Minkyu, Suh Hyunsuk, Cho Eun-Jung, Buratowski Stephen

Abstract excerpt

The C-terminal domain (CTD) of Rpb1, the largest subunit of RNA polymerase II, acts as a binding platform for various mRNA processing and histone-modifying enzymes that act co-transcriptionally. These factors are targeted to specific phosphorylation states of the CTD that predominate at different stages of transcription. Within the repeating sequence YSPTSPS, serines 2 and 5 are major phosphorylation sites, but...

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Identifiers

PMID: 19679665
DOI: 10.1074/jbc.M109.028993
PMCID: PMC2785330

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Source receipt: pubmed, retrieved 7 Sept 2026.

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