Article
Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations.
The American journal of clinical nutrition - 1 Dec 2014
Dashti Hassan S, Shea M Kyla, Smith Caren E, Tanaka Toshiko, Hruby Adela, Richardson Kris, Wang Thomas J, Nalls Mike A, Guo Xiuqing, Liu Yongmei, Yao Jie, Li Dalin, Johnson W Craig, Benjamin Emelia J, Kritchevsky Stephen B, Siscovick David S, Ordovás José M, Booth Sarah L
Abstract excerpt
BACKGROUND: Poor vitamin K status is linked to greater risk of several chronic diseases. Age, sex, and diet are determinants of circulating vitamin K; however, there is still large unexplained interindividual variability in vitamin K status. Although a strong genetic component has been hypothesized, this has yet to be examined by a genome-wide association (GWA) study. OBJECTIVE: The objective was to identify...
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