Article
β-Carotene 15,15'-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent.
The American journal of clinical nutrition - 1 Dec 2012
Hendrickson Sara J, Hazra Aditi, Chen Constance, Eliassen A Heather, Kraft Peter, Rosner Bernard A, Willett Walter C
Abstract excerpt
BACKGROUND: Carotenoids have been hypothesized to reduce the risk of many diseases, but associations with intakes or blood concentrations may arise from other constituents of fruit and vegetables. Use of genetic variation in β-carotene 15,15'-monooxygenase 1 (BCMO1), a key enzyme in provitamin A carotenoid metabolism, as a surrogate for carotenoid exposure may aid in determining the role of carotenoids...
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