Article

Common and rare genetic variation intersects with ancestry to influence human skin and plasma carotenoid concentrations

2024-12-23

Abstract excerpt

<h4>ABSTRACT</h4> Carotenoids are dietary bioactive compounds with health effects that are biomarkers of fruit and vegetable intake. Here, we examine genetic associations with plasma and skin carotenoid concentrations in two rigorously phenotyped human cohorts (n=317). Analysis of genome-wide SNPs revealed heritability to vary by genetic ancestry (h²=0.08–0.44) with ten SNPs at four loci reaching genome-wide signi...

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Literature Corpus work: 591d0c63-1e4d-58c2-a24a-f7a22fbc7fd8
DOI: 10.1101/2024.12.20.24319465

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