Article
Genome-wide association study identifies common variants associated with circulating vitamin E levels.
Human molecular genetics - 1 Oct 2011
Major Jacqueline M, Yu Kai, Wheeler William, Zhang Hong, Cornelis Marilyn C, Wright Margaret E, Yeager Meredith, Snyder Kirk, Weinstein Stephanie J, Mondul Alison, Eliassen Heather, Purdue Mark, Hazra Aditi, McCarty Catherine A, Hendrickson Sara, Virtamo Jarmo, Hunter David, Chanock Stephen, Kraft Peter, Albanes Demetrius
Abstract excerpt
In genome-wide association studies (GWAS) of common genetic variants associated with circulating alpha- and gamma-tocopherol concentrations in two adult cohorts comprising 5006 men of European descent, we observed three loci associated with alpha-tocopherol levels, two novel single-nucleotide polymorphisms (SNPs), rs2108622 on 19pter-p13.11 (P= 1.7 × 10(-8)) and rs11057830 on 12q24.31 (P= 2.0 × 10(-8)) and...
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