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Article

VKORC1-dependent pharmacokinetics of intravenous and oral phylloquinone (vitamin K1) mixed micelles formulation.

European journal of clinical pharmacology - 1 Mar 2013

Marinova Milka, Lütjohann Dieter, Breuer Olof, Kölsch Heike, Westhofen Philipp, Watzka Matthias, Mengel Martin, Stoffel-Wagner Birgit, Hartmann Gunther, Coch Christoph, Oldenburg Johannes

Abstract excerpt

OBJECTIVE: The pharmacokinetics of phylloquinone (vitamin K1) were evaluated in healthy human adult volunteers (15 male and 15 female) following oral and intravenous administration of a mixed micelles formulation (Konakion MM 2 mg) in an open label study design. The subjects were allocated to one of three genotype-specific groups (n = 10 in each group) in terms of VKORC1 promoter polymorphism c.-1639 G > A to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Injections, Intravenous

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Source

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Identifiers

PMID: 22864379
DOI: 10.1007/s00228-012-1362-y
PMCID: PMC3572390

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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