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Article

Circulating Phylloquinone and the Risk of Four Female-Specific Cancers: A Mendelian Randomization Study.

Nutrients - 29 Oct 2024

Yalew Melaku, Mulugeta Anwar, Lumsden Amanda L, Madakkatel Iqbal, Lee S Hong, Oehler Martin K, Mäenpää Johanna, Hyppönen Elina

Abstract excerpt

BACKGROUND: Observational studies have linked vitamin K and cancer, but the causality of this association remains unknown. This Mendelian randomization (MR) study aims to investigate the association between circulating phylloquinone (vitamin K1) levels and four female-specific cancers. METHODS: We used four single-nucleotide polymorphisms (SNPs) to instrument phylloquinone, with the reported F-statistic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39519513
DOI: 10.3390/nu16213680
PMCID: PMC11547380

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