Article
Role of IFN-γ and IL-6 cytokines and their association in determining susceptibility to chronic idiopathic urticaria.
Genetic testing and molecular biomarkers - 1 Dec 2014
Alasandagutti Madhavi Latha, Ponnana Meenakshi, Sivangala Ramya, Thada Shruthi, Joshi Lavanya, Hussain Hidayath, Ansari Soheb Sadath, Valluri Vijayalakshmi, Gaddam Suman Latha
Abstract excerpt
Chronic Idiopathic Urticaria (CIU) is a common skin disorder, which may occur spontaneously. The aim of the present study was to assess the serum levels of interferon (IFN)-γ and interleukin (IL)-6 and to examine the association of IFN-γ+874 T/A and IL-6-174 G/C cytokine gene polymorphisms. To accomplish this, ELISA-based cytokine serum levels of IFN-γ (n=30) and IL-6 (n=30) in CIU patients (n=100) and Healthy...
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