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Article

Role of cytokine gene (IFN-γ, TNF-α, TGF-β1, IL-6, and IL-10) polymorphisms in pathogenesis of acute rheumatic fever in Turkish children.

European journal of pediatrics - 1 Jul 2012

Col-Araz Nilgun, Pehlivan Sacide, Baspinar Osman, Oguzkan-Balci Sibel, Sever Tugce, Balat Ayse

Abstract excerpt

UNLABELLED: Acute rheumatic fever (ARF) is a delayed immunologically mediated sequela of throat infection by group A β-hemolytic streptococci. Inflammatory cytokines may play a pathogenic role in ARF. The objective of this study was to investigate the potential associations between interferon (IFN)-γ, interleukin (IL)-6, tumor necrosis factor (TNF)-α, transforming growth factor (TGF)-β1, and IL-10 gene...

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PMID: 22350281
DOI: 10.1007/s00431-012-1689-5

Genes

TNF
CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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