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Article

Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian population.

BMC medical genetics - 3 Jul 2020

Hanaei Sara, Abdollahzade Sina, Sadr Maryam, Mirbolouk Mohammad Hossein, Fattahi Ehsan, Khoshnevisan Alireza, Rezaei Nima

Abstract excerpt

BACKGROUND: Intervertebral disc degeneration (IVDD) is an age-related degenerative disease, presenting with low back pain or radicular pain. The inflammatory changes would occur in discs in the process of IVDD. Therefore, the inflammatory and anti-inflammatory cytokines, as well as their respective genes, have been proposed to play roles in pathophysiology of disease. This study has been conducted to elucidate...

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Identifiers

PMID: 32620160
DOI: 10.1186/s12881-020-01081-3
PMCID: PMC7333426

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