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Article

Polymorphisms in cytokine genes IL6, TNF, IL10, IL17A and IFNG influence susceptibility to complicated skin and skin structure infections.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Dec 2014

Stappers M H T, Thys Y, Oosting M, Plantinga T S, Ioana M, Reimnitz P, Mouton J W, Netea M G, Joosten L A B, Gyssens I C

Abstract excerpt

Complicated skin and skin structure infections (cSSSIs) are caused by Gram-positive and Gram-negative, aerobic and anaerobic pathogens, with a polymicrobial aetiology being frequent. Recognition of invading pathogens by the immune system results in the production of pro- and anti-inflammatory cytokines, which are extremely important for intercellular communication and control of infection. This study assessed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25022448
DOI: 10.1007/s10096-014-2201-0

Genes

TNF
IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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