Article
Interleukin-6 and tumor necrosis factor-alpha gene polymorphisms in chronic idiopathic urticaria.
Allergologia et immunopathologia - 1 Jan 2000
Tavakol M, Amirzargar A A, Movahedi M, Aryan Z, Bidoki A Z, Gharagozlou M, Aghamohammadi A, Nabavi M, Ahmadvand A, Behniafard N, Heidari K, Soltani S, Rezaei N
Abstract excerpt
BACKGROUND: This study was performed to evaluate association of gene polymorphisms among proinflammatory cytokines and susceptibility to chronic idiopathic urticaria (CIU). METHODS: Ninety patients with prolonged urticaria more than 6 weeks were included as case group. Single nucleotide polymorphisms (SNPs) of IL-6 (G/C -174, G/A nt565) and TNF-α (G/A -308, G/A -238) were evaluated, using polymerase chain...
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