Article
Genetic predisposition to parthenium dermatitis in an Indian cohort due to lower-producing genotypes of interleukin-10 (-) 1082 G>A and (-) 819 C>T loci but no association with interferon-γ (+) 874 A>T locus.
The British journal of dermatology - 1 Jul 2011
Khatri R, Mukhopadhyay K, Verma K K, Sethuraman G, Sharma A
Abstract excerpt
BACKGROUND: Parthenium dermatitis is an activated T cell-mediated type IV hypersensitivity. Its pathogenesis is well characterized, with interindividually varying serum levels of pro- and anti-inflammatory and regulatory T-cell cytokines and coherently perturbed cross-regulation between them. The functional single nucleotide polymorphisms (SNPs) in these cytokine genes might function as risk/susceptibility...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.