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Article

Polymorphisms of the receptor for advanced glycation end-products and glyoxalase I in patients with renal cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2015

Chocholatý Matúš, Jáchymová Marie, Schmidt Marek, Havlová Klára, Křepelová Anna, Zima Tomáš, Babjuk Marko, Kalousová Marta

Abstract excerpt

The receptor for advanced glycation end products (RAGE) and its ligands are involved in the pathogenesis of cancer. Glyoxalase I (GLO1) is an enzyme which detoxifies advanced glycation end product (AGE) precursors. The aim of the study was to find out the relationship between four polymorphisms (single nucleotide polymorphism, SNP) of the RAGE gene (AGER) and one SNP of the GLO1 gene and clear cell renal cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25407489
DOI: 10.1007/s13277-014-2821-0

Genes

GLO1
AGER

Variants

rs1800625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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