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Article

A419C (E111A) polymorphism of the glyoxalase I gene and vascular complications in chronic hemodialysis patients.

Annals of the New York Academy of Sciences - 1 Apr 2008

Kalousová Marta, Germanová Alexandra, Jáchymová Marie, Mestek Oto, Tesar Vladimír, Zima Tomás

Abstract excerpt

Advanced glycation end products (AGEs) take part in the pathogenesis of vascular, diabetic, and uremic complications. Their precursors are detoxified by the glyoxalase system. Our aim was to study A419C (E111A) single nucleotide polymorphism (SNP) of the glyoxalase I gene in hemodialysis (HD) patients. A419C SNP, several laboratory parameters including soluble receptor for AGEs (sRAGE), and clinical data were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18079478
DOI: 10.1196/annals.1433.012

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