Article
Receptor for advanced glycation end products (RAGE) polymorphisms are associated with systemic lupus erythematosus and disease severity in lupus nephritis.
Lupus - 1 Aug 2012
Martens H A, Nienhuis H L A, Gross S, van der Steege G, Brouwer E, Berden J H M, de Sévaux R G L, Derksen R H W M, Voskuyl A E, Berger S P, Navis G J, Nolte I M, Kallenberg C G M, Bijl M
Abstract excerpt
OBJECTIVE: Interaction of advanced glycation end products (AGEs) with their receptors (RAGE) plays an important role in inflammation in auto-immune diseases. Several functional polymorphisms of RAGE have been described. In this study we analysed the role of RAGE polymorphisms in disease susceptibility for systemic lupus erythematosus (SLE). In addition, we investigated whether these polymorphisms in SLE are...
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