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Article

Transmembrane domains of attraction on the TSH receptor.

Endocrinology - 1 Feb 2015

Latif Rauf, Ali M Rejwan, Mezei Mihaly, Davies Terry F

Abstract excerpt

The TSH receptor (TSHR) has the propensity to form dimers and oligomers. Our data using ectodomain-truncated TSHRs indicated that the predominant interfaces for oligomerization reside in the transmembrane (TM) domain. To map the potentially interacting residues, we first performed in silico studies of the TSHR transmembrane domain using a homology model and using Brownian dynamics (BD). The cluster of dimer...

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Identifiers

PMID: 25406938
DOI: 10.1210/en.2014-1509
PMCID: PMC4298320

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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