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Article

Marked microevolution of a unique Mycobacterium tuberculosis strain in 17 years of ongoing transmission in a high risk population.

PloS one - 1 Jan 2014

Mehaffy Carolina, Guthrie Jennifer L, Alexander David C, Stuart Rebecca, Rea Elizabeth, Jamieson Frances B

Abstract excerpt

The transmission and persistence of Mycobacterium tuberculosis within high risk populations is a threat to tuberculosis (TB) control. In the current study, we used whole genome sequencing (WGS) to decipher the transmission dynamics and microevolution of M. tuberculosis ON-A, an endemic strain responsible for an ongoing outbreak of TB in an urban homeless/under-housed population. Sixty-one M. tuberculosis isolates...

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Identifiers

PMID: 25405861
DOI: 10.1371/journal.pone.0112928
PMCID: PMC4236100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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