Article
Mycobacterium tuberculosis--heterogeneity revealed through whole genome sequencing.
Tuberculosis (Edinburgh, Scotland) - 1 May 2012
Ford Chris, Yusim Karina, Ioerger Tom, Feng Shihai, Chase Michael, Greene Mary, Korber Bette, Fortune Sarah
Abstract excerpt
The emergence of whole genome sequencing (WGS) technologies as primary research tools has allowed for the detection of genetic diversity in Mycobacterium tuberculosis (Mtb) with unprecedented resolution. WGS has been used to address a broad range of topics, including the dynamics of evolution, transmission and treatment. Here, we have analyzed 55 publically available genomes to reconstruct the phylogeny of Mtb,...
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