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Article

RNA interference and antiviral therapy

1 Jan 2007

Abstract excerpt

RNA interference (RNAi) is an evolutionally conserved gene silencing mechanism present in a variety of eukaryotic species. RNAi uses short double-stranded RNA (dsRNA) to trigger degradation or translation repression of homologous RNA targets in a sequence-specific manner. This system can be induced effectively in vitro and in vivo by direct application of small interfering RNAs (siRNAs), or by expression of short...

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PMID: 17876887
DOI: 10.3748/wjg.v13.i39.5169

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