Article
RNA interference technologies and therapeutics: from basic research to products.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy - 1 Jan 2009
López-Fraga Marta, Martínez Tamara, Jiménez Ana
Abstract excerpt
RNA interference (RNAi) is a natural cellular process that regulates gene expression by a highly precise mechanism of sequence-directed gene silencing at the stage of translation by degrading specific messenger RNAs or blocking translation. In recent years, the use of RNAi for therapeutic applications has gained considerable momentum. It has been suggested that most of the novel disease-associated targets that...
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