Article
SLC29A1 (ENT1) polymorphisms and outcome of complete remission in acute myeloid leukemia.
Cancer chemotherapy and pharmacology - 1 Sept 2016
Kim Jeong-Hyun, Lee Chansu, Cheong Hyun Sub, Koh Youngil, Ahn Kwang-Sung, Kim Hyung-Lae, Shin Hyoung Doo, Yoon Sung-Soo
Abstract excerpt
PURPOSE: The solute carrier family 29 (equilibrative nucleoside transporter), member 1 (SLC29A1) is known to be involved in the transportation and resistance of the nucleoside analog cytosine arabinoside (AraC), one of the most effective drugs in the treatment of acute myeloid leukemia (AML). METHODS: In vitro functional analysis in AML cells and genetic association study were performed. RESULTS: Our functional...
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