Article
Acrylamide-induced molecular mutation spectra at HPRT locus in human promyelocytic leukaemia HL-60 and NB4 cell lines.
Mutagenesis - 1 Jul 2008
Ao Lin, Liu Sheng-Xue, Yang Meng-Su, Fong Chi-Chun, An Hui, Cao Jia
Abstract excerpt
Acrylamide (AA) is a compound widely used in many industries around the world. The recent finding that it is formed naturally in foods by heating raises human health concerns. AA is a proven carcinogen in animals and a probable carcinogen in humans, while its mutagenicity detected using in vitro mammalian gene mutation assays is still inconsistent in different cell systems. In the present study, we investigated...
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