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Article

Association of the COMT val158met variant with antidepressant treatment response in major depression.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2008

Baune Bernhard T, Hohoff Christa, Berger Klaus, Neumann Anna, Mortensen Sünke, Roehrs Tilmann, Deckert Jürgen, Arolt Volker, Domschke Katharina

Abstract excerpt

In several previous biochemical, pharmacological, and genetic studies, the catechol-O-methyltransferase (COMT) has been suggested to be involved in the pathogenesis as well as the pharmacological treatment of affective disorders. In the present study, 256 patients with major depression (DSM-IV) o...

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Source

Identifiers

PMID: 17522626
DOI: 10.1038/sj.npp.1301462

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17522626-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of the COMT val158met variant with antidepressant treatment response in major depression.PMID 17522626Read ↗

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