Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder.

doi:10.1016/j.psychres.2009.03.010

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Article

Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder.

Psychiatry research - 30 Mar 2010

Illi Ari, Setälä-Soikkeli Eija, Kampman Olli, Viikki Merja, Nuolivirta Timo, Poutanen Outi, Huhtala Heini, Mononen Nina, Lehtimäki Terho, Leinonen Esa

Abstract excerpt

The functional val108/158met polymorphism of the COMT gene (rs4680) was evaluated in major depressive disorder (MDD), and in the treatment response to antidepressants in MDD. We could not demonstrate any significant difference in the distribution of this COMT single-nucleotide polymorphism (SNP)...

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PMID: 20071037
DOI: 10.1016/j.psychres.2009.03.010

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COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20071037-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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